Instead of the compression of morbidity we should all be aiming for, diabetics are risk for expansion of morbidity with age-related diseases appearing much earlier in life than they should Glycation is responsible, and whenever blood sugar is elevated, glycation is occurring. Now normal people have low levels of hemoglobin ArC. In fact, the upper limit of normal is set at 6 percent of total hemoglobin. Amounts greater than that suggest Pre-diabetes or frank diabetes, requiring lifestyle modifications or medications to keep blood sugar in the normal range more of the time. As with oxidative stress, we have defense mechanisms to protect Muscle might from the low level of glycation resulting from normal processing of food and distribution of caloric energy.